Generic Name: Sildenafil
Brand Name: Viagra

Sildenafil structure

Popular medicines with Sildenafil

What is Sildenafil

Sildenafil Citrate is an FDA-approved drug, primarily recommended to treat impotence in males, also known as Erectile Dysfunction (ED). 

As a generic Viagra, it helps men achieve and maintain a firm erection during sexual activity. 

Sildenafil Citrate containing pills are more commonly known as blue pills. 

What is Sildenafil used for

Erectile Dysfunction is a sexual dysfunction when the man is unable to get and keep an erection during sexual activity. 

In combination with sexual stimulation, Sildenafil Citrate increases the blood flow through the penis and helps a man get an erection.

Blue pills help men achieve and maintain a firm erection during sexual activity. Hence, successfully treating ED. 

How does Sildenafil work

Sildenafil belongs to a group of Phosphodiesterase Type 5 (PDE5) inhibitors. 

When a man is sexually stimulated, the body’s normal response is to increase the blood through the penis, which results in an erection. 

Pills containing Sildenafil have vasodilatory effects and relax the muscles of the blood vessels in the penile region. 

It restricts the PDE5 enzyme, responsible for the penis becoming flaccid. 

Hence, by restricting the release of PDE5 and vasodilating the blood vessels of the penis, the blue pills help men get and maintain a firm erection. 

Sildenafil Dosage 

Sildenafil dosage for ED depends on the severity of the condition. It has to be taken exactly as prescribed by the medical professional. 

The Sildenafil pills are usually taken 30 minutes to 1 hour before the sexual activity. It works for up to 4 hours after the intake. 

There are different strengths of Sildenafil Citrate, which is prescribed according to age, medical history, and disorder severity.

It is available as conventional tablets, chewable pills, and oral jelly.  

One should take Sildenafil pills only once a day. One can take it with or without food. 

However, high-fat meals affect the working of Sildenafil Citrate. Hence, avoid it while using the pills. 

Also, the salt is also available in combination with Dapoxetine to treat Premature Ejaculation. 

Who can take Sildenafil Citrate

The pills are safe for intake by men suffering from ED, aged 18 and above. The strength of pills might be different for different individuals. 

However, pills with salt to treat ED are not recommended for use in women and children. Lovegra is a similar medicine safe to use in women. 

Sildenafil Citrate Side effects

Like all medications, Sildenafil Citrate can cause side effects, although the frequency of side effects is low. 

Common Side Effects of Sildenafil

The prevalence of common Sildenafil side effects is as low as 0.01%. The symptoms are mild and occur for a few moments. If in case the symptoms do not go away, please consult the doctor immediately 

  • Headache
  • Face Flushing 
  • Nausea
  • Dizziness
  • Stuffy nose 

Rare Side Effects 

These rare side effects occur in less than 1 in 1000 people. Contact your doctor immediately if you experience symptoms like 

  • Seizures
  • Prolonged or painful erection 

How to reduce the side effects of Sildenafil?

The mild side effects of Sildenafil Citrate either tend to go in a few hours or can be quickly relieved. Side effects like flushing, dizziness, and headache can go away with proper resting. 

For Nausea and Vomiting, you can administer Vomistop to get relief.

Sildenafil Interactions 

Drug Interactions

Some medicines might react with Sildenafil Citrate to show side effects. Hence, before taking the blue pill, inform your doctor if you accept, 

  • Nitrates
  • Diuretics
  • Antifungal medicines 
  • Medicines for treating AIDS

Also, avoid taking other ED medicines like Tadalafil and Vardenafil as they might lead to an overdose. 

The blue pills can also react with vitamin and herbal tablets. Hence, please consult your doctor before administering any of them. 

Disease Interactions

There are a few disease interactions with Sildenafil Citrate, which include 

  • Renal Dysfunction 
  • Priapism
  • Cardiovascular Disease
  • Alcoholism 
  • Liver Disorders
  • Retinitis Pigmentosa
  • Seizure Disorders

Food and Beverage Interactions

Sildenafil interaction with any of the following may cause an increased risk of certain side effects, 

  • Alcohol
  • Tobacco
  • Grapefruit
  • Grapefruit Juice
  • Pomelo Juice

Sildenafil Warnings and Precautions 

  • One should avoid taking Sildenafil for treatment ED if they are allergic to the salt 
  • One should avoid smoking and alcohol intake while taking this medicine
  • Sildenafil causes dizziness. Hence, avoid driving and using heavy machinery while on the medicine. 

Pros and Cons of Sildenafil

Pros Cons
It is a first-choice medication for treating Impotence in men. People who have suffered a stroke or heart attack in the last six months cannot take this medicine. 
Sildenafil does not need to be used daily to be effective; take it only when needed.People who do not follow the proper prescription may experience side effects. 
It is an endothelial-friendly medicine and has led to fewer heart attacks and better erection.
It starts working under 30 minutes to 1 hour of intake. 
It is a much cheaper and equally effective alternative to Viagra. 


Store the medicine in a cool, dry place away from direct sunlight. 

Similar Salts

There are other salts that are PDE5 inhibitors and work the same as Sildenafil Citrate, which includes 

Other Products with Similar Salts

Frequently Asked Questions

What happens when you take Sildenafil?

Sildenafil relaxes the muscles of blood vessels in the penile region. Hence, increasing the blood flow and helping men get and maintain an erection. Sildenafil starts working after 30 minutes to 1 hour of intake.

Is it OK to take Sildenafil every day?

Yes, if your doctor has prescribed a daily dose of Sildenafil, you can take it daily. Sildenafil is an FDA-approved drug for treating Erectile Dysfunction and is safe to consume daily.

Is Sildenafil as good as Viagra?

Yes, generic Viagra, also known as Sildenafil, works similarly to Viagra but at a cheaper cost. It may appear different, but it is still an effective ED medication.

What happens if you take Sildenafil with alcohol?

Sildenafil can decrease blood pressure, and combining it with alcohol may increase this effect. You may be more likely to experience dizziness, lightheadedness, fainting, flushing, headache, and heart palpitations.

What happens if you take 2 Sildenafil?

You should always take Sildenafil according to your doctor’s recommendations. An overdose of the ED tablets can induce severe headaches, low blood pressure, and orthostasis (blood pressure drop when standing), which can lead to fainting. Higher dosages can also cause Priapism, a painful erection lasting more than 4 hours.

How long does it take for Sildenafil to take effect?

Sildenafil generally starts working for Erectile Dysfunction within 30 minutes after consumption. It works for up to 4 hours, while its action is usually reduced after 2 hours.

Can you buy the blue pill over the counter in the USA?

No, Sildenafil and other ED medications are prescription-based medicines. Hence, they are not available over the counter in the US. 

Should you take Sildenafil if you don’t need it?

Over 80% of men with ED may get an erection after taking the ED medicine. Millions of men who have taken these medications appropriately and safely have experienced a positive response. However, you don’t need them if you don’t have ED.

Do you build a tolerance for Sildenafil?

No, when taken as directed, Sildenafil stays effective and retains its potency.

What happens if a woman takes Sildenafil?

Sildenafil is an FDA-approved drug only to be used in men. The medicine might cause severe blood flow through the genital region, low blood pressure, and other side effects in women. Hence, it should not be consumed by women.