Sildenafil Dosage: A Guide to Achieving Optimal Results

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Written By Julie Ingram
Sildenafil dosage recommendations

Sildenafil, also known as Viagra, is a medication primarily used to treat Erectile Dysfunction (ED).

Sildenafil is also used for treating Pulmonary Arterial Hypertension (PAH). 

It is an effective treatment for ED and PAH. But the effectiveness and safety of Sildenafil depend on taking the correct dosage. 

This article will discuss the dosages of Sildenafil and how to take the medication.

We will also elaborate on the factors affecting Sildenafil dosage. 

Sildenafil Dosage

The appropriate dosage of Sildenafil (Viagra) depends on the specific medical condition and needs. 

FDA has approved Sildenafil for treating two medical conditions – Erectile Dysfunction and Pulmonary Arterial Hypertension. Therefore, the Sildenafil dosage for each condition is different. 

Here, we will provide a detailed discussion of the dosage for both conditions.

Did you know that Sildenafil was not originally developed for ED management? Explore its transformative journey into an ED medication in this articleThe history of Sildenafil and its development

Sildenafil Dosage for Erectile Dysfunction 

FDA has approved three doses of Sildenafil for Erectile Dysfunction. These include: 

  • 25mg
  • 50mg
  • 100mg

Sildenafil, used for treating ED, comes in an oral tablet form. And it should only be used by males above 18 years of age. 

1. 25 mg dose of Sildenafil 

The lowest dose of Sildenafil is 25mg. Doctors prescribe this dose if 

  • You have mild Erectile Dysfunction 
  • You are experiencing side effects on taking 50 or 100mg dose of Sildenafil
  • You are using medicines like Alpha-blockers, etc., or have other medical conditions
  • You are above 65 years of age

2. 50mg of Sildenafil 

The most recommended starting dose of Sildenafil for Erectile Dysfunction is 50mg. 

This Sildenafil dosage has a good balance of effectiveness and tolerability. During trials, it has shown effectiveness in 74% of males.

Doctors prescribe a 50mg dose of Sildenafil in case of moderate Erectile Dysfunction. 

Depending on the individual’s response and tolerability, the dose can be increased to 100mg or decreased to 25mg. 

3. 100mg dose of Sildenafil 

100mg is the maximum dose of Sildenafil that the FDA approves. 

It is the most effective dose prescribed for severe Erectile Dysfunction. But it may increase the dose-related side effects like sudden hearing or vision changes. 

This highest dose gets prescribed if you are not responding to a 50mg dose.

Wondering about getting a Sildenafil prescription? Find the guidance in this articleHow to get a Sildenafil Prescription: Your Ultimate Guide

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  • Sildenafil Dosage for Pulmonary Arterial Hypertension 

    For treating Pulmonary Arterial Hypertension (PAH), Sildenafil dosage ranges between 10mg to 80mg. Among these, 20mg is the most recommended dose. 

    It can be used for PAH treatment in adults and children over one year of age.

    But the Sildenafil dosage varies, depending on the individual’s weight and age.

    Age GroupRecommended DosageMaximum Dosage
    Adults20mg orally, 3 times a dayUp to 80mg orally, 3 times a day
    Children (1 year and older, weighing 45 kg or more)20mg orally, 3 times a dayUp to 40mg orally, 3 times a day
    Children (1 year and older, weighing 20 to 45 kg)20mg orally, 3 times a day
    Children (1 year and older, weighing 20 kg or less)10mg orally, 3 times a day

    How to Take Sildenafil

    Consult a doctor to know about dosageSource: Africa_Images
    Consult a doctor to know about dosage

    Sildenafil is a prescription-based medication. This is due to its potential to interact and cause side effects. 

    So, you should always take Sildenafil as your doctor prescribes.

    For Erectile Dysfunction

    • Take it 30-60 minutes before sexual activity as Sildenafil takes time to start working
    • Swallow the whole pill with water. Avoid chewing or breaking the tablet
    • Do not take more than one pill in 24 hours unless advised by your doctor
    • Take the dose as soon as you recall in case of missed doses. But do not take the missed dose if your next dose is approaching
    • In case of overdose, consult the doctor immediately

    For Pulmonary Arterial Hypertension

    • Take the recommended dose three times a day at 4-6 hours apart
    • If you have missed the Sildenafil dosage, take it as soon as you remember. In case your next dose is due, do not take the dose you missed
    • If you have overdosed on Sildenafil, talk to your doctor right away

    Curious to know if taking Sildenafil without a prescription is safe or not? Get the answer in this articleSildenafil without a prescription: Is it safe

    Sildenafil for Pulmonary Arterial Hypertension is available in different forms also, like oral suspensions and injectable forms. Dosage recommendations for these forms of Sildenafil may differ from oral tablets. It is advisable to consult a doctor to determine the appropriate dosage.

    Factors Affecting the Dosage of Sildenafil

    Various factors can affect the Sildenafil dosage. These include age, weight, medical conditions, etc. 

    Here are some of the key factors discussed in detail.


    Age is a significant factor in determining the appropriate Sildenafil dosage for both ED and PAH. 


    Body weight is a determining factor in Sildenafil dosage for Pulmonary Arterial Hypertension. Individuals with higher body weight require a higher dosage to achieve the desired effect. 

    But the Sildenafil dosage for Erectile Dysfunction does not get affected by the weight of the individual. 

    Medical History

    Certain medical conditions, like liver or kidney diseases, can affect how the body metabolizes Sildenafil. This may require a lower dosage to avoid potential side effects

    This can affect the dosage for both ED and PAH. 

    Other Medications

    Some medications interact with Sildenafil. This can affect its effectiveness or increase the risk of side effects. 

    When determining the appropriate dosage for ED and PAH, doctors consider all the medications an individual takes.

    Individual response to Sildenafil varies. Due to this, the doctor may adjust the dosage based on how an individual responds to the medication.

    We have provided you with well-researched, general information. But it is always advisable that you should consult a doctor to get personalized advice.


    In summary, the effectiveness and safety of Sildenafil depend on its right dosage.

    The appropriate dosage depends on several factors, like age, weight, and overall health. 

    Sometimes, Sildenafil doses for ED exceeding 100mg may be prescribed off-label by the doctor. 

    It is essential to consult with a doctor to determine the proper dosage and frequency of use.

    With the right dosage and appropriate use, Sildenafil can treat ED and PAH effectively.

    It’s not just about the dosage—various factors can impact how well Sildenafil works. Learn the best practices for using the medication in this articleMastering Sildenafil: How to Use it for the Best Results

    Frequently Asked Questions

    What is Sildenafil, and how does it work?

    Sildenafil is a medication used to treat Erectile Dysfunction (ED) in males. The FDA has also approved it for treating Pulmonary Arterial Hypertension (PAH). 
    It works by dilating blood vessels in the body. Thus, allowing for increased blood flow. This improves the quality of erections and reduces blood pressure in the arteries.

    What is the recommended Sildenafil dosage?

    The recommended starting dose of Sildenafil for ED is 50mg. Depending on its effectiveness and tolerability, the doctor may increase the dose to 100mg or decrease it to 25mg. 
    For PAH, the Sildenafil dose varies according to the age and weight of the individuals. So, consult your doctor to determine the right dosage.

    Can Sildenafil be taken with food?

    Yes, you can take Sildenafil with or without food. But do not take it with a high-fat meal as it delays the absorption of Sildenafil in the body. 
    It also reduces its highest concentration in the blood by 29%. Therefore, take Sildenafil on an empty stomach for fast absorption and the strongest effects.

    Are there any side effects of Sildenafil?

    Although Sildenafil is a safe medicine, it has the potential to cause side effects. Some of its common side effects include headaches, facial flushing, and indigestion. 
    They are temporary and require minimal to no medical attention. You can avoid these adverse effects by following your doctor’s prescription properly.

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