How Does the Blue Pill Work

Published On
Updated On
Written By Julie Ingram
how does the blue pill work

The Blue Pill is the popular name given to the brand-name medicine Viagra.

It is a medication that is used to treat Erectile Dysfunction (ED) in men or Assigned Males at Birth (AMAB). 

ED is the inability of men or AMAB to get and sustain a firm erection during sexual intercourse.

Developed by the pharmaceutical company Pfizer, it has been a revolutionary breakthrough in the field of sexual health. 

This article will provide a complete understanding of how does the Blue Pill work to treat ED in men. We will also discuss the mechanism of action of the Blue Pill in women.

Mechanism of action of the Blue Pill

The Blue Pill, also known as Viagra, contains an active ingredient called Sildenafil Citrate.

Sildenafil belongs to a category of medicines known as Phosphodiesterase Type 5 (PDE5) inhibitors. 

Its mechanism of action revolves around enhancing the effects of Nitric Oxide (NO).

NO is a natural chemical in the body that promotes increased blood flow and facilitates an erection.

To better understand how the Blue Pill works, let’s break down the process into several steps:

1. Nitric Oxide Release

During sexual stimulation, the body releases Nitric Oxide (NO).

NO acts as a signaling molecule and starts the process of penile erection.

Nitric Oxide helps in the production of cyclic Guanosine Monophosphate (cGMP).

2. cGMP and Smooth Muscle Relaxation

cGMP is a molecule that causes the smooth muscle cells within the penis to relax. 

This relaxation allows the blood vessels in the penis to dilate, which increases blood flow to the penis.

Thus, filling the erectile tissues with blood induces a firm erection.

3. Role of PDE5 enzyme

Phosphodiesterase Type 5 (PDE5) is an enzyme present in the penis. It is responsible for breaking down cGMP and terminating erection. 

PDE5 enzyme converts cGMP into its inactive form, limiting the duration of the erection.

4. PDE5 Inhibition

The Blue Pill (Viagra), as a PDE5 inhibitor, blocks the action of the PDE5 enzyme. 

This blocking prevents the breakdown of cGMP. 

Thus, helping to maintain higher levels of cGMP in the erectile tissues and enabling dilation of the penile blood vessels.

PDE5 inhibitors like the Blue Pill (Viagra) has the potential to interact and cause side effects. Therefore, consulting a doctor before taking the medication is necessary.

5. Erection Maintenance

The dilation of the penile blood vessels increases blood flow to the penis.

As a result, a firm and sustained erection gets induced. 

This allows individuals with Erectile Dysfunction to engage in sexual activity for longer. 

Checkout Cart:
Ignite the Spark in Your Relationship with the Blue Pill (Viagra).
Check out the generic versions of Viagra at Fordaily Medicine and make a choice today:

  • Shop Cenforce
  • Shop Kamagra
  • Shop Suhagra
  • Does the Blue Pill work for all types of Erectile Dysfunction

    Man suffering from depressionSource: tommaso79_from_Getty_Images

    The Blue Pill is effective in treating Erectile Dysfunction that is caused by physical factors, particularly those that restrict blood flow to the penis. 

    It may not be fully effective in addressing ED that is caused by psychological factors like Depression or Anxiety. 

    These psychological factors reduce the sexual desire of individuals, which leads to the development of psychogenic ED. 

    While the Blue Pill can improve the physical aspects of achieving an erection, it does not directly address conditions affecting sexual desire.

    It is important to understand that sexual desire is a complex interplay of physiological and psychological factors. 

    The Blue Pill focuses on improving the physical aspects of ED, such as facilitating blood flow to the penis and promoting an erection. 

    Sometimes, psychogenic ED is caused due to sexual performance anxiety. In that case, the Blue Pill (Viagra) may help by boosting your sexual confidence. 


    The Blue Pill, or Viagra, has been a game-changer in the treatment of Erectile Dysfunction. 

    By inhibiting the PDE5 enzyme, it allows for increased blood flow to the penis and facilitates a firm and long-lasting erection. 

    However, it is essential to remember that the Blue Pill is a prescription medication. It should only be taken under the guidance of a doctor.

    It is crucial to discuss any concerns or medical conditions with a doctor before starting this medication.

    Order Now
    Take Your Pleasure to New Heights!
    Discover the Power of the generic versions of Viagra (Sildenafil).  

    Frequently Asked Questions

    How long does it take for the Blue Pill to work?

    The onset of action varies among individuals, but typically the Blue Pill starts working within 30 minutes to an hour after ingestion. 
    However, it is important to note that sexual stimulation is still necessary for the medication to produce an erection.

    Can women take the Blue Pill?

    The Food and Drug Administration has not given approval to use the Blue Pill in women. 
    But doctors sometimes prescribe it to treat women’s sexual dysfunction. This is known as the off-label use of the Blue Pill in women. 
    However, the medicine known as Lovegra, containing Sildenafil, is prescribed to women.

    How does the Blue Pill work to treat women’s sexual dysfunction?

    It is belived that the Blue Pill (Viagra) increases blood flow to the clitoris. This improved blood flow increases vaginal sensitivity, which helps women to experience a fulfilling sexual intercourse.

    Are there any potential side effects?

    Like any medication, the Blue Pill (Viagra) can have side effects. Commonly reported side effects include headache, facial flushing, indigestion, and nasal congestion. 
    In rare cases, severe side effects such as Priapism (prolonged and painful erection) and sudden hearing or vision loss have been reported.

    Is the Blue Pill safe to use with other medications?

    The Blue Pill can interact with other medical conditions like Nitrates and Alpha-blockers. These interactions can cause side effects and even lead to life-threatening complications. 
    It is important to consult a doctor before taking the Blue Pill (Viagra). The doctor helps you determine whether the Blue Pill is safe for you to use or not.

    When quoting information, Fordaily Medicine always provides full citations. Please read our Content Information Policy if you want more details on the methods we take to ensure the continued high quality of our content.