Explore the Right Dosage of Tadalafil for Maximum Benefits

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Written By Julie Ingram
Dosage of Tadalafil

Tadalafil is a medication that is approved to treat three medical conditions: Erectile Dysfunction (ED), Benign Prostatic Hyperplasia (BPH), and Pulmonary Arterial Hypertension (PAH). 

It belongs to a group of medications called PDE5 inhibitors and has gained recognition for its effectiveness, safety, and high tolerability among patients.

To harness its full potential, it is crucial to understand the right dosage of Tadalafil. 

This comprehensive guide will provide you with valuable insights into the different dosing options available for Tadalafil. It will also address the factors that doctors consider when adjusting dosages.

Understanding dosage of Tadalafil

Tadalafil is available in tablet form with different strengths, i.e., 2.5mg, 5mg, 10mg, and 20mg. 

As mentioned, the Food and Drug Administration (FDA) has approved it for treating three different conditions ED, BPH, and PAH. 

Since each condition requires a specific dosing regimen, it is crucial to understand the different available doses. 

Doing so can ensure that you take the right dosage tailored to your specific medical needs. 

This understanding is essential for your safety, as it helps minimize the risk of potential side effects that might arise from incorrect dosing.

Now, let’s delve into the details of the dosages for each condition. 

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  • Tadalafil dosage for Erectile Dysfunction (ED)

    Erectile Dysfunction (ED) is an inability of men or Assigned Males at Birth (AMAB) to get and maintain a firm erection. 

    Tadalafil, commonly known as Cialis, is an effective and well-tolerated medicine for those seeking effective ED treatment.  

    The FDA has approved two types of Tadalafil dosages for Erectile Dysfunction. These include the “as-needed dose” and the “once-daily dose.”

    1. As-needed dose of Tadalafil 

    The recommended starting dose for most men is 10 mg. This “as-needed” dose is taken when required approximately 30 minutes before engaging in sexual intercourse. 

    It can remain effective in your system for up to 36 hours, earning it the nickname “the Weekend Pill.” 

    If your doctor finds that the 10mg dose is not producing desired effects or causing side effects, they may suggest adjusting the dose. 

    The doctor either increases it to 20 mg if needed or reduces it to 5 mg if you experience any unwanted effects.

    2. Once-daily dose of Tadalafil 

    For the “once-daily” dosing regimen, Tadalafil is taken at a lower dose consistently every day, regardless of sexual activity. 

    This dose must be taken at the same time each day to maintain a steady level of the medication in the body. 

    The recommended starting dose for once-daily use is 2.5mg. 

    Depending on your body’s response and tolerability, your doctor might consider increasing the daily dose to 5mg.

    The 5mg Cialis dose is the maximum dose that can be taken daily for ED. 

    Tadalafil dosage for Benign prostatic Hyperplasia (BPH)

    BPH is a condition that involves the enlargement of the prostate gland. It causes urinary symptoms like slow urine flow, difficulty starting and stopping urine, etc.

    For treating BPH, the recommended dosage of Tadalafil is 5mg which must be taken once daily for up to 26 weeks. 

    The medication is usually taken at the same time each day. Unlike the as-needed approach, the daily dosage ensures a steady level of the medication in the body. 

    This helps to improve urinary symptoms associated with BPH. 

    Tadalafil dosage for Pulmonary Arterial Hypertension (PAH)

    Man suffering from Pulmonary Arterial HypertensionSource: Goads Agency from Getty Images Signature
    Man suffering from Pulmonary Arterial Hypertension

    PAH is characterized by high blood pressure in the lungs’ arteries. Thus, causing the symptoms like shortness of breath, fatigue, etc. 

    Tadalafil is sold under the brand name Adcirca for treating Pulmonary Arterial Hypertension. 

    For treating PAH, the recommended dosage of Tadalafil is higher than that used for Erectile Dysfunction and BPH. 

    The starting dose for PAH is 40 mg (two 20 mg tablets) taken once daily. It is not recommended to divide the 40mg dose over the course of the day. 

    Some individuals may be prescribed a lower initial dose of 20 mg (one 20 mg tablet) daily, depending on their condition and tolerability. 

    Avoid taking more than one Tadalafil dose in 24 hours unless recommended by your doctor.

    Factors requiring Tadalafil dosage adjustment

    Various factors may cause the need to adjust the Tadalafil dosage. 

    These include response to the treatment, conditions’ severity, medical interactions, age, overall health status, etc. 

    Here we discuss each factor requiring the dosage adjustment in detail. 

    1. Response to Treatment

    Some individuals may be more sensitive to Tadalafil, while others may require higher doses to achieve the desired outcome. 

    Doctors may adjust the dosage based on how a patient responds to existing treatment.

    2. Severity of Condition

    The severity of the condition being treated, like the extent of ED, the size of the prostate in BPH, or the stage of PAH, may influence the initial dose and subsequent adjustments.

    3. Medication Interactions

    Tadalafil can interact with other medications, like Nitrates or Alpha-blockers. These drug interactions may necessitate dosage adjustments. 

    This will ensure the safe and effective use of the medication.

    4. Age

    Age-related changes in metabolism and health can impact how Tadalafil is metabolized in the body. Elderly individuals may require lower or less frequent doses to avoid potential side effects.

    5. Frequency of Use

    For as-needed dosing, the frequency of sexual activity may influence the dosage prescribed. 

    Less frequent involvement in sexual activities might require lower doses to avoid drug accumulation in the body. 

    6. Overall health

    Body weight can influence drug metabolism, and individuals with higher body weight may require higher doses to achieve the desired effect.

    Similarly, certain medical conditions like liver or kidney disease affect drug metabolization and clearance. Dosage adjustments may be necessary in these cases to ensure safety and effectiveness.

    It is essential to consult a doctor to adjust the dosage. It should not be done without medical intervention.


    Tadalafil is a versatile medication for treating Erectile Dysfunction (ED), Benign Prostatic Hyperplasia (BPH), and Pulmonary Arterial Hypertension (PAH). 

    For ED, the starting dose is 10mg, with possible adjustments based on individual response. 

    For treating BPH, a daily 5mg dose is taken at the same time, while PAH requires a 40 mg once-daily dosage. 

    Various factors like metabolism, health conditions, tolerance, etc., can influence the need to adjust the existing Tadalafil dosage. 

    It is crucial to consult a doctor to determine the right dosage and for adjusting it according to each specific case.

    Be it Erectile Dysfunction or Pulmonary Arterial Hypertension, Tadalafil has got you covered!

    Frequently Asked Questions

    Can I adjust the timing of Tadalafil intake based on my sexual activity schedule?

    Yes, you can adjust the timing of tadalafil intake for the as-needed dose based on your sexual activity schedule. However, make sure to take the medication 30 minutes before sexual activity for optimal effectiveness.

    What if I miss a daily dose of Tadalafil for Benign Prostatic Hyperplasia?

    If you miss a daily dose of Tadalafil for Benign Prostatic Hyperplasia (BPH), take it as soon as you remember. But, if the time of your next scheduled dose is close, then skip the missed dose and continue with the regular dosing schedule.

    Is it safe to split Tadalafil tablets for the once-daily dose?

    It is not recommended to split Tadalafil tablets for the once-daily dose. Always take the prescribed full tablet to ensure consistent dosing. It will also ensure that the appropriate amount of medication stays in your system throughout the day.

    What should I do if I have overdosed on Tadalafil?

    If you suspect an overdose of Tadalafil or experience severe side effects like severe dizziness, fainting, or Priapism (prolonged erection), seek immediate medical attention. It is essential to get immediate medical assistance in the event of a medication overdose.

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