Exploring the Use of Tadalafil for the Long Term ED Treatment

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Written By Julie Ingram
Tadalafil for the long term

Erectile Dysfunction (ED) is a common sexual condition affecting 30 million men in the US alone. 

ED is the inability of men or Assigned Males at Birth (AMAB) to get and maintain a firm erection. 

Tadalafil, known by its brand name Cialis, is a widely prescribed medication for ED due to its long-lasting effects and unique dosing option. 

As men seek a reliable and effective solution for their ED, the question of using Tadalafil for long-term management arises. 

This article will explore the effectiveness and risks of using Tadalafil for the long term. We will also elaborate on safety considerations that need to be considered while using this medication for extended periods. 

How long can you use Tadalafil safely

Tadalafil has shown safety and efficacy in treating Erectile Dysfunction. However, the exact duration for which it can be safely used cannot be answered. 

This is because most of the studies have deemed it safe and effective for a period of up to 24 months. 

Within this timeframe, many individuals have experienced positive results and improved erectile function. 

However, beyond the two-year mark, the effectiveness and safety of using Tadalafil for the long term have not been extensively studied.

As a result, the question of how long “ongoing” usage can be considered safe is still unanswered. 

This answer may vary based on individual factors such as the response to the treatment and the overall safety profile of each person.

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  • Effectiveness of using Tadalafil for long term

    Extensive clinical studies have investigated the effectiveness of using Tadalafil for periods of up to 24 months. 

    The results of these studies have been promising. Thus, indicating that daily use of Tadalafil for the long term can effectively treat Erectile Dysfunction (ED).

    In another clinical trial, men who took a daily 5mg dose of Tadalafil for six months experienced improvements in their erectile function compared to those who received a placebo (another medicine).

    Moreover, the benefits of using Cialis extend beyond treating ED. Daily consumption of 5mg Tadalafil over the long term has shown positive results in reducing the hardening of arteries or slowing down its progression. 

    Additionally, it has demonstrated positive effects in reducing urinary symptoms associated with Benign Prostatic Hyperplasia (BPH).

    Although the above findings are all positive, further research on the long-term effectiveness of Tadalafil is necessary. 

    It is essential to remember that individual responses may vary, and Tadalafil might not be equally effective for everyone.

    Risks of using Tadalafil for the long term

    There may be risks of experiencing side effects and developing tolerance to using Tadalafil for the long term. 

    1. Side Effects

    Side effects of Tadalafil due to long term useSource: Africa images
    Man Suffering from Back Pain

    Tadalafil is a well-tolerated and safe medicine for long-term use of up to 24 months. Nevertheless, like any medication, it can cause side effects. 

    As per research, a daily 5mg dose of Cialis for ED treatment caused adverse effects like Nausea, headache, flushing, and muscle and lower back pain. 

    Most of these side effects are mild and subside over time as the body adapts to the medication.

    2. Tolerance 

    There is a concerning risk of developing tolerance with the long-term use of Tadalafil.

    Over time, some individuals may develop tolerance, meaning their current or initial dosage might become less effective. In such cases, a higher dosage may be required to achieve the desired results. 

    However, increasing the dosage can also raise the risk of potential side effects.

    If any adverse reactions persist or become concerning, it is crucial to contact a doctor immediately.

    Safety considerations for long term use of Tadalafil

    1. Medical Assessment

    Before starting Tadalafil or any long-term medication, a comprehensive medical assessment is crucial. 

    Discuss your medical history, current health conditions, and any medications you are taking with your doctor.

    Certain health issues, like heart conditions or liver problems, may require caution or alternative treatments.

    2. Dosage and Timing

    Follow the prescribed dosage and dosing schedule provided by your doctor. 

    Avoid altering the dosage or frequency without medical guidance. 

    Taking too much Tadalafil or using it more frequently than recommended can increase the risk of side effects.

    3. Avoid Nitrate Medications or ALpha-blockers

    Do not take Tadalafil if you are currently using Nitrates for chest pain or Alpha-blockers. 

    Combining Tadalafil with these medications can lead to a severe drop in blood pressure, which can be life-threatening.

    4. Regular Check-ups

    Regularly check in with your doctor to monitor the effectiveness and safety of long-term Tadalafil use. 

    This allows for adjustments in dosage or treatment plans if needed.


    Tadalafil is an effective and safe treatment option for men dealing with Erectile Dysfunction. 

    When used for long-term management, it has shown positive results for many individuals. 

    However, studies have been conducted to evaluate the use of Tadalafil for up to 24 months. 

    Further research is needed to validate the effectiveness and safety of using Tadalafil for the long term beyond 24 months. 

    As with any medication, it is crucial to consult a doctor to determine the most appropriate treatment plan for your specific needs. 

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    Frequently Asked Questions

    Can I adjust the Tadalafil dosage on my own?

    No, you should never adjust the Tadalafil dosage on your own. Any changes to your treatment plan should be discussed with and approved by your doctor.

    What should I do if I experience side effects while using Tadalafil long-term?

    If you experience any side effects while using Tadalafil, like headaches, wait for them to subside, as most of the effects are mild and temporary. 

    However, if they cause you concerns, contact your doctor. They can assess the severity of the side effects and recommend appropriate measures.

    Can I drink alcohol while using Tadalafil long-term?

    It is best to control alcohol consumption while using Tadalafil for the long term, as excessive alcohol intake can increase the risk of side effects. It also reduces the effectiveness of the medication.

    Can Tadalafil lose its effectiveness over time? 

    Some individuals may experience a decrease in the effectiveness of Tadalafil over extended use. It may be a sign of developing tolerance to the medication. 

    If you notice reduced effectiveness, consult your doctor to determine potential solutions or alternative treatments.

    Are there any age restrictions for using daily Tadalafil?

    Tadalafil is a medication formulated to treat Erectile Dysfunction (ED) and is suitable for men aged 18 years and older. 

    As a result, men in this age group may be prescribed daily Tadalafil for the management of ED.

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