Exploring the Use of Tadalafil in Men with High Blood Pressure

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Written By Julie Ingram
Tadalafil in men with high blood pressure

Erectile Dysfunction (ED) can be a real challenge for men or Assigned Males at Birth (AMAB). 

ED is the inability of men or AMAB to get and maintain a firm erection during sexual activity. 

Fortunately, various Erectile Dysfunction medicines have been introduced, including Tadalafil.

Tadalafil, known by its brand name Cialis, is an effective and well-tolerated ED pill for most men.

However, a noteworthy consideration arises for men who are dealing with both ED and Hypertension (high blood pressure).

This article delves into the effectiveness and safety of using Tadalafil in men with high blood pressure. It aims to address the question of whether or not this medication can enhance erectile function in men without worsening their Hypertension condition.

Effectiveness of Tadalafil in Men with High Blood Pressure

High blood pressure or Hypertension damages blood vessels and reduces Nitric Oxide (NO) production.

This leads to inadequate blood flow to the penis and causes Erectile Dysfunction in men or AMAB. 

Tadalafil is an effective medicine used to treat Erectile Dysfunction caused by impeded blood flow. Thus, helping men with high blood pressure to get and maintain firm erections. 

As per studies, a lower dose of Tadalafil in men with Hypertension offers a dual benefit—improving both ED and blood pressure control. 

This is because Cialis works by dilating blood vessels, which increases blood flow to the penis and lowers blood pressure. 

Another study suggested that a high dose of Tadalafil (20mg) can even lower blood pressure in patients with uncontrolled Hypertension.

Thus, suggesting that Tadalafil can be a viable option for men with both ED and high blood pressure. 

Individual responses to Tadalafil can vary. Therefore, consulting a doctor is crucial to determine its effectiveness and safety for each case.

Risks of Using Tadalafil in Men with High Blood Pressure

Although Tadalafil effectively improves erectile function, its use in men with Hypertension carries certain inherent risks.

These risks include the possibility of encountering side effects and potential interactions with antihypertensive medications.

Let’s dig deeper to understand the risks linked to the use of Tadalafil in men with high blood pressure. 

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  • Interactions of Tadalafil with Antihypertensive Medicines

    Alpha-blockers, ACE inhibitors, Beta-blockers, Calcium channel blockers, etc., are various medicines used to manage high blood pressure. These are known as antihypertensive drugs. 

    As per a study, Tadalafil can be safely used in patients who are also taking antihypertensive medications.

    It was found that there were no significant differences in blood pressure between patients who took combined Tadalafil with antihypertensive medicine and those who did not. 

    While these findings are encouraging, more research is needed to validate these claims. 

    However, a need for caution emerges if using Tadalafil with Doxazosin, which is an Alpha-blocker. 

    Certain Alpha-blockers interact with Cialis. Thus, potentially causing a dangerous drop in blood pressure if used together, which can be hazardous.

    Moreover, minor interaction also exists between Tadalafil and Lisinopril, which is an ACE inhibitor. 

    In a nutshell, while some antihypertensive medication are safe to take with Tadalafil, others pose contraindications. 

    Therefore, it is important to consult a doctor to make informed choices about using Cialis along with specific antihypertensive medications. 

    Interaction of Tadalafil with Alpha-blockers can be life-threatening. Thus, it is advisable to avoid taking these two medicines together.

    Side Effects of Using Tadalafil in Men with Hypertension

    Man suffering from muscle aches while using Tadalafil with high blood pressureSource: tommaso79 from Getty Images
    men suffering from a muscle aches

    The use of Tadalafil in men with Hypertension can give rise to various side effects.

    These side effects can range from common to rare effects. The interplay between Tadalafil and the pre-existing blood pressure condition might influence these adverse effects. 

    Common adverse effects of Cialis are headache, indigestion, muscle aches, and flushing.

    These effects 1 out of 100 people and are mild and temporary. They subside once the body adjusts itself to the dosage of the medication. 

    Tadalafil also has the potential to cause serious side effects like Priapism (painful erection for more than 4 hours), low blood pressure, vision changes, cardiovascular risks, etc. 

    These serious adverse effects are rare and occur in 1 out of 1000 people but may be more concerning for men taking antihypertensive drugs. 

    Therefore, it is advisable to always have open communication with your doctor to determine the safety of the medication. 

    Safety Considerations

    Men with Hypertension should take some safety measures before using Tadalafil. 

    These include consultation with a doctor, regular follow-ups, awareness about medicine’s interactions, etc. 

    1. Consultation with a doctor

    Men with both ED and high blood pressure should consult a doctor before taking Tadalafil.

    They will assess your overall health, including your blood pressure levels and any other medical conditions you might have.

    2. Blood Pressure Monitoring

    Men with high blood pressure should have their blood pressure well-controlled before considering Tadalafil. 

    It is recommended to frequently monitor blood pressure, both before and after starting the medication.

    3. Be Aware of Medication Interactions and Side Effects

    Tadalafil can interact with certain antihypertensive medications and can lead to adverse effects.

    It is important to provide your doctor with a complete list of all the medications you are currently taking to avoid potential interactions.

    4. Cardiovascular Health

    Tadalafil can have an effect on the cardiovascular system.

    So, it is important for men with high blood pressure to have a complete cardiovascular checkup before using the medication.


    The use of Tadalafil in men with high blood pressure has shown effectiveness in treating ED without exacerbating the blood pressure condition. 

    In fact, Tadalafil works by dilating blood vessels, which lowers blood pressure. This has been a positive factor in dealing with high blood pressure.

    While it is well-tolerated in men with Hypertension, it is not free from risks. It can potentially interact with certain antihypertensive medicine and cause adverse effects. 

    Therefore, consultation with a doctor before starting Cialis treatment is crucial to determine the safety of the medication for your use.

    Frequently Asked Questions

    What should I do if I experience side effects while using Tadalafil?

    If you experience any side effects while using Tadalafil, especially if you have high blood pressure, consult your doctor immediately.

    Can Tadalafil replace antihypertensive medications?

    No, Tadalafil is not a replacement for antihypertensive medications. It primarily addresses Erectile Dysfunction, and its impact on blood pressure is a secondary benefit.

    How frequently can I use Tadalafil?

    Tadalafil comes in different dosages with varying usage recommendations. It can be used once daily or whenever required. 

    Always consult a doctor and follow the instructions regarding dosage and frequency.

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